From the sidelines to the battlefield

1. Kontos AP, Jorgensen-Wagers K, Trbovich AM, et al. Association of Time Since Injury to the First Clinic Visit With Recovery Following Concussion. JAMA Neurol. 2020;77(4):435–440.
   
2. Raab CA, Peak AS, Knoderer C. Half of Purposeful Baseline Sandbaggers Undetected by ImPACT's Embedded Invalidity Indicators. Arch Clin Neuropsychol. 2020 Apr 20;35(3):283-290.
   
3. Resch JE, Brown CN, Schmidt J, Macciocchi SN, Blueitt D, Cullum CM, Ferrara MS. The sensitivity and specificity of clinical measures of sport concussion: three tests are better than one. BMJ Open Sport Exerc Med. 2016 Jan 19;2(1):e000012.  
4. O’Brien, A. M., Casey, J. E., & Salmon, R. M. (2017). Short-term test–retest reliability of the ImPACT in healthy young athletes. Applied Neuropsychology: Child, 1–9. doi:10.1080/21622965.2017.1290529
   
5. Nelson LD, Temkin NR, Dikmen S, et al. Recovery After Mild Traumatic Brain Injury in Patients Presenting to US Level I Trauma Centers: A Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) Study. JAMA Neurol. 2019;76(9):1049‐1059.
   
6. Bazarian JJ,McClung J, Cheng YT, FlesherW, Schneider SM. Emergency department management of mild traumatic brain injury in the USA. Emerg Med J. 2005;22(7):473-477. 

Using the same EEG data acquired for the Structural Injury Classifier, BrainScope also provides an objective assessment of brain function impairment, including concussion, with the Brain Function Index (BFI) algorithm. The BFI includes only EEG features, especially those that measure changes in “connectivity” between brain regions, reflecting the physiological changes seen in concussion.

The BFI is expressed as a percentile of a non head-injured population, from 0 to 100, with a lower score showing higher levels of impairment. This enables clinicians to make more confident clinical diagnoses of concussion using objective physiological data.

In the FDA validation study, the Brain Function Index was demonstrated to scale with severity of functional impairment: as the BFI goes down, the level of functional impairment increases. The assessment is indicated for use on patients 18-85 years of age, within 72 hours of head injury, and GCS 13-15.

Read more in our Publications & Papers

The Concussion Index (CI) assessment incorporates easily acquired EEG data, cognitive performance testing, and specific clinical signs/symptoms into a multimodal algorithm to objectively assess concussion, with the largest contribution from EEG features only.

In the FDA Validation study, the CI was demonstrated to have high accuracy in identifying the likelihood of concussion within 72 hours of injury. The CI is expressed as an index from 0 to 100 with a lower score indicating greater severity of injury. Injured patients with CIs less than or equal to the threshold (70) are classified as Likely Concussed, and those with CIs greater than the threshold are classified as Not Likely Concussed. The assessment is indicated for use on patients 13-25 years of age and GCS 15.

Read more in our Publications & Papers

Neurocognitive Assessments

The BrainScope® device includes a customizable battery of five cognitive performance tests, which are performed by the patient on the handheld device. These tests measure several cognitive functions including visuomotor reaction time, simple motor speed, working memory, and response control. Results can be calculated in comparison to normative data based on the non head-injured population of the same age and gender and in comparison to previous results for that patient using a reliable change index computation.

Digitized Assessments

To supplement the EEG-based and cognitive performance assessments, BrainScope has digitized several standard clinical assessments commonly used by clinicians to assess head-injured patients. The digitized assessments are completed on the handheld and results for selected assessments are included in the patient PDF report and are displayed with their original intended formatting.
Digitized Assessments include:

• PECARN Decision Rule
• Sports Concussion Assessment Test (SCAT5)
• Military Acute Concussion Evaluation (MACE 2)
• Near Point Convergence (NPC) and others.

Read more in our Publications & Papers