Aids in ruling out the likelihood of a brain bleed in ~15 minutes.
BrainScope's Structural Injury Classifier (SIC) algorithm assesses the likelihood of a brain bleed to even the smallest detectable amount of blood (≥1mL) with 99% sensitivity and a 98% negative predictive value (NPV) and a 60% reduction in unnecessary head CTs has been reported.
BrainScope aids in the evaluation and management of concussion, enabling earlier treatment which is associated with reduced time to recovery.
BrainScope's Concussion Index (CI) algorithm incorporates rapidly acquired EEG data, cognitive performance testing, and specific clinical signs/symptoms into a multimodal algorithm to assess concussion, with the largest contribution from EEG features, especially those reflecting changes in "connectivity" between brain regions. The CI aids in objective clinical diagnosis and reflects concussion severity.
The BrainScope Brain Function Index (BFI) algorithm includes only EEG features, especially those reflecting the physiological changes seen in concussion in the acute injury stage. The BFI scales with clinical severity.
To supplement the brain electrical activity based algorithms and cognitive performance assessments, BrainScope has digitized several standard clinical assessments commonly used by clinicians to evaluate head-injured patients, including MACE 2. These assessments can be performed directly on the BrainScope device and uploaded to the patient's electronic health record.
Abstract
Introduction
Military units lack the ability to quickly, objectively, and accurately assess individuals that have suffered a closed head injury for structural brain injury and functional brain impairments in forward settings, where neurological assessment equipment and expertise may be lacking. With acute traumatic brain injury patients, detached medical providers are often faced with a decision to wait and observe or medically evacuate, both of which have cascading consequences.
Structural brain injury assessment devices, when employed in forward environments, have the potential to reduce the risk of undiagnosed and/or mismanaged traumatic brain injuries given their high negative predictive value and suggested increased specificity compared to common subjective clinical decision rules. These handheld devices are portable and have an ease of use, from combat medic to physician, allowing for use in austere environments, safely keeping soldiers with their teams when able and suggesting further evaluation via computed tomography (CT) scan when warranted.
Methods
Data collected on 13 encounters at 5 locations were retrospectively analyzed using descriptive statistics.
Results
A total number of 13 examinations were performed using the BrainScope One device during the 9-month deployment. The Structural Injury Classification was negative for 11 of the patients. Two of the 11 patients underwent head CT scans, which confirmed the absence of intracranial hemorrhage. Of the two positive Structural Injury Classification exams, one was CT negative and no CT was performed for the other based on clinical judgment.
Conclusion
The data from this study suggest that structural brain injury devices may provide value by ruling out serious brain injury pathology while limiting excessive medical evacuations from austere settings, where neurological assessment equipment and expertise may be lacking, reducing unnecessary head CT scans.
Developed in part with funding from the Department of Defense with over 12 years of evidence-based research and development, eight separate DoD research contracts, and two GE NFL Head Health Challenge awards
Improve short and long-term outcomes (including psychological health) with early detection and intervention
Appropriate removal from duty / activity when injured
Reduce wait times for diagnosis
Improve safety by reducing unnecessary radiation exposure from CTs
Objective standard to help identify and stratify patients
May be administered by Combat Medics / Corpsmen
Fast triage to help rule out life-threatening structural injury
Assess for concussion with same inputs
Enable timely referrals, treatment plans, and continuity of care
Reduce clinical assessment time and increase throughput
Incorporate assessment tools currently used by the military
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